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Decision-making in mania: A PET study

Abstract:

Poor decision-making is often observed clinically in the manic syndrome. In normal volunteers, decision-making has been associated with activation in the ventral prefrontal cortex and the anterior cingulate gyrus. The aim of this study was to evaluate task-related activation in bipolar manic patients in these regions of the prefrontal cortex using PET. Six subjects with mania, 10 controls and six subjects with unipolar depression (an affective patient control group) were scanned using the bol...

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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Role:
Author
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Journal:
Brain
Volume:
124
Issue:
12
Pages:
2550-2563
Publication date:
2001-01-01
ISSN:
0006-8950
URN:
uuid:a4ef4bcf-7540-48fc-a82d-321fe75c5943
Source identifiers:
223182
Local pid:
pubs:223182

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