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Characterisation of the low affinity interaction between rat cell adhesion molecules CD2 and CD48 by analytical ultracentrifugation.

Abstract:

CD2 is a cell adhesion molecule found on the plasma membrane of T-lymphocytes. Its counter-receptor in rat is the structurally related CD48. This interaction is believed to contribute to the adhesion of T-cells to other cells such as cytotoxic targets and antigen presenting cells. Cell-cell adhesion involves the formation of multiple cell adhesion molecule complexes at the cell surface and if cell-cell de-adhesion is to occur, these complexes need to be disrupted. The affinities of cell adhes...

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Publication status:
Published

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Publisher copy:
10.1007/s002490050060

Authors


Silkowski, H More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine
Barclay, AN More by this author
Harding, SE More by this author
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Volume:
25
Issue:
5-6
Pages:
455-462
Publication date:
1997
DOI:
EISSN:
1432-1017
ISSN:
0175-7571
URN:
uuid:a4aa7b3f-f470-48ea-9c74-cfe3e704dfdf
Source identifiers:
16080
Local pid:
pubs:16080

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