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From Standardization to Adaptation: Clinical Trials and the Moral Economy of Anticipation

Abstract:

Hailed as the gold standard, the Randomized Controlled Trial (RCT) occupies a hegemonic position at the top of Evidence Based Medicine's hierarchy of knowledge. It is testament to the methodology's capacity for standardization that it can so readily be spoken of in the singular: the RCT. Under what conditions, then, is it possible to speak of change in the gold standard? Since the 1950s, alternative versions of the RCT have been advocated for under the banner of 'adaptive design'. Adaptiv...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Author Accepted Manuscript

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Publisher copy:
10.1080/09505431.2016.1255721

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Department:
Oxford, MSD, Primary Care, Primary Care Health Sciences
Publisher:
Taylor & Francis Publisher's website
Journal:
Science as Culture Journal website
Volume:
26
Issue:
2
Pages:
232–254
Publication date:
2016-11-14
DOI:
EISSN:
1470-1189
ISSN:
0950-5431
Pubs id:
pubs:661888
URN:
uri:a4819326-e7b9-4b62-aa56-129541dde998
UUID:
uuid:a4819326-e7b9-4b62-aa56-129541dde998
Local pid:
pubs:661888

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