Fractional exhaled Nitric Oxide monitoring in paediatric asthma management

Journal article

An annual review is recommended for children with asthma but objective measures of control are lacking (1). Monitoring exacerbations and a symptom score are both suggested, but the widely used Children’s Asthma Control Test (C-ACT) has a positive predictive value of only 46.7% for asthma exacerbations at the recommended score of <24/27 (2). Additional tests such as Peak Expiratory Flow or Spirometry have not been shown to improve quality of life or symptom scores compared to symptom-based management (3). FeNO may provide additional information, such as quantifying eosinophilic airway inflammation to identi-fy patients more likely to benefit from an adjustment in their ICS regimen over other treatment options.

Authors: Jones, N; Wang, K; Yang, Y; Heneghan, C; Price, C

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Royal College of General Practitioners
• Journal: British Journal of General Practice
• Volume: 67
• Issue: 664
• Pages: 531-532
• Publication date: 2017-10-26
• Acceptance date: 2017-04-05
• DOI: 10.3399/bjgp17X693449
• EISSN: 1478-5242
• ISSN: 0960-1643