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Journal article

The immunomodulatory role of syncytiotrophoblast microvesicles.

Abstract:

Immune adaptation is a critical component of successful pregnancy. Of primary importance is the modification of cytokine production upon immune activation. With the discovery that normal pregnancy itself is a pro-inflammatory state, it was recognised that the classical Th1/Th2 cytokine paradigm, with a shift towards 'type 2' cytokine production (important for antibody production), and away from 'type 1' immunity (associated with cell mediated immunity and graft rejection), is too simplistic. ...

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Publication status:
Published

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Journal:
PloS one
Volume:
6
Issue:
5
Pages:
e20245
Publication date:
2011-01-01
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
URN:
uuid:a4664512-16e3-4360-9c9a-b7ffe10d428f
Source identifiers:
314645
Local pid:
pubs:314645

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