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Supercoils in human DNA.

Abstract:

The three-dimensional structure of a double-stranded DNA molecule may be described by distinguishing the helical turns of the DNA duplex from any superhelical turns that might be superimposed upon the duplex turns. There are characteristic changes in the hydrodynamic properties of superhelical DNA molecules when they interact with intercalating agents. The hydrodynamic properties of nuclear structures released by gently lysing human cells are changed by intercalating agents in this characteri...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Journal of cell science
Volume:
19
Issue:
2
Pages:
261-279
Publication date:
1975-11-05
EISSN:
1477-9137
ISSN:
0021-9533
URN:
uuid:a40711b8-f988-413d-a4a0-d1713ae1ee1c
Source identifiers:
16704
Local pid:
pubs:16704

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