Journal article icon

Journal article

Recognition of a signal peptide by the signal recognition particle.

Abstract:

Targeting of proteins to appropriate subcellular compartments is a crucial process in all living cells. Secretory and membrane proteins usually contain an amino-terminal signal peptide, which is recognized by the signal recognition particle (SRP) when nascent polypeptide chains emerge from the ribosome. The SRP-ribosome nascent chain complex is then targeted through its GTP-dependent interaction with SRP receptor to the protein-conducting channel on endoplasmic reticulum membrane in eukaryote...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1038/nature08870

Authors


Expand authors...
Journal:
Nature
Volume:
465
Issue:
7297
Pages:
507-510
Publication date:
2010-05-05
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:a3e114bb-85ff-44e4-93bc-4cab0f188b4b
Source identifiers:
59338
Local pid:
pubs:59338

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP