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Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial.

Abstract:

OBJECTIVE: To assess the magnitude and independence of the effects of routine blood pressure lowering and intensive glucose control on clinical outcomes in patients with long-standing type 2 diabetes. RESEARCH DESIGN AND METHODS: This was a multicenter, factorial randomized trial of perindopril-indapamide versus placebo (double-blind comparison) and intensive glucose control with a gliclazide MR-based regimen (target A1C

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Publisher copy:
10.2337/dc09-0959

Authors


Zoungas, S More by this author
de Galan, BE More by this author
Ninomiya, T More by this author
Grobbee, D More by this author
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Journal:
Diabetes care
Volume:
32
Issue:
11
Pages:
2068-2074
Publication date:
2009-11-05
DOI:
EISSN:
1935-5548
ISSN:
0149-5992
URN:
uuid:a3cd6eb2-e505-4922-af13-1ef03a19ac58
Source identifiers:
215661
Local pid:
pubs:215661

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