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Automatic comparison and classification of protein structures.

Abstract:

The classification and alignment of multiple three-dimensional protein structures is a powerful way to detect similarities that cannot be discovered from the sequences alone and can help to infer phylogeny. However, the alignment process remains problematic for divergent structures. We have devised a fully automatic pipeline, HSF, drawing its inspiration from well-known structural alignment methods, which given a list of structures not only aligns all pairs but also classifies them fully. We ...

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Publication status:
Published

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Publisher copy:
10.1016/j.jsb.2013.05.007

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Structural Biology
Role:
Author
Journal:
Journal of structural biology
Volume:
183
Issue:
1
Pages:
47-56
Publication date:
2013-07-05
DOI:
EISSN:
1095-8657
ISSN:
1047-8477
URN:
uuid:a330bdaf-ef82-4c3d-b9a9-dd5240e82c04
Source identifiers:
405700
Local pid:
pubs:405700

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