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Automatic comparison and classification of protein structures.

Abstract:

The classification and alignment of multiple three-dimensional protein structures is a powerful way to detect similarities that cannot be discovered from the sequences alone and can help to infer phylogeny. However, the alignment process remains problematic for divergent structures. We have devised a fully automatic pipeline, HSF, drawing its inspiration from well-known structural alignment methods, which given a list of structures not only aligns all pairs but also classifies them fully. We ...

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Publication status:
Published

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Publisher copy:
10.1016/j.jsb.2013.05.007

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Structural Biology
Role:
Author
Journal:
Journal of structural biology
Volume:
183
Issue:
1
Pages:
47-56
Publication date:
2013-07-01
DOI:
EISSN:
1095-8657
ISSN:
1047-8477
Source identifiers:
405700
Language:
English
Keywords:
Pubs id:
pubs:405700
UUID:
uuid:a330bdaf-ef82-4c3d-b9a9-dd5240e82c04
Local pid:
pubs:405700
Deposit date:
2013-11-17

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