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THE DERMO-EPIDERMAL INTERFACE IN LICHEN-PLANUS END LUPUS-ERYTHEMATOSUS

Abstract:

The pathogenesis of lichen planus (LP) and cutaneous lupus erythematosus (LE) was investigated by immunohistochemical staining of skin biopsies from eight patients with these conditions compared with controls. Monoclonal antibodies were directed against antigens of the various components of the basement membrane zone. We found a differential, site specific response by these components to the inflammatory process. The structural collagens in the basal lamina underwent a primarily reparative re...

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Publication status:
Published

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Authors


DEBERKER, D More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
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Journal:
EUROPEAN JOURNAL OF DERMATOLOGY
Volume:
4
Issue:
1
Pages:
58-62
Publication date:
1994-01-05
ISSN:
1167-1122
URN:
uuid:a30703c2-e622-49fb-a09c-5960cb4ba0f9
Source identifiers:
5624
Local pid:
pubs:5624

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