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Journal article

Sclerosing cholangitis

Abstract:

Primary sclerosing cholangitis is a chronic cholestatic liver disease of unknown etiology that leads to progressive obliterative fibrosis of the biliary tree. The disease progresses in most patients to death from liver failure or cholangiocarcinoma. The etiology remains obscure, but immune-mediated factors are thought to be involved in its pathogenesis, as suggested by the strong HLA associations and a circulating antineutrophil cytoplasmic antibody. The neutrophil antigen remains unknown, an...

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Publication status:
Published

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Authors


Martins, E More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Journal:
CURRENT OPINION IN GASTROENTEROLOGY
Volume:
12
Issue:
5
Pages:
466-470
Publication date:
1996-09-05
DOI:
ISSN:
0267-1379
URN:
uuid:a2fe8930-cad9-46ef-9f4c-de29f19410ad
Source identifiers:
171705
Local pid:
pubs:171705
Language:
English

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