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A randomised controlled trial of the effects of albendazole in pregnancy on maternal responses to mycobacterial antigens and infant responses to bacille Calmette-Guérin (BCG) immunisation [ISRCTN32849447]

Abstract:

Background: Maternal schistosomiasis and filariasis have been shown to influence infant responses to neonatal bacille Calmette-Guérin (BCG) immunisation but the effects of maternal hookworm, and of de-worming in pregnancy, are unknown.

Methods: In Entebbe, Uganda, we conducted a randomised, double-blind, placebo-controlled trial of a single dose of 400 mg of albendazole in the second trimester of pregnancy. Neonates received BCG. Interf...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1471-2334-5-115

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
NPEU
Role:
Author
Publisher:
BioMed Central
Journal:
BMC Infectious Diseases More from this journal
Volume:
5
Article number:
115
Publication date:
2005-12-21
Acceptance date:
2005-12-21
DOI:
EISSN:
1471-2334
Language:
English
Keywords:
UUID:
uuid:a2eb73ef-aefc-401d-ba63-ed67925c8839
Local pid:
pubs:484108
Source identifiers:
484108
Deposit date:
2014-09-18

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