Conference item
SPECT imaging and biodistribution studies of 111In-EGF-Au-PEG nanoparticles in vivo
- Abstract:
- Radiolabelled antibodies and peptides hold promise for molecular radiotherapy but are often limited by low payload resulting in delivery of inadequate amounts of radioactivity to tumour tissue and, therefore, modest therapeutic effect. We have developed PEGylated epidermal growth factor (EGF)-gold nanoparticles (NP) with a high indium-111 (111In) payload (111In-EGF-Au-PEG NPs) as a prototypic NP-based theranostic radiopharmaceutical.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 182.9KB, Terms of use)
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- Publisher copy:
- 10.1186/s41181-016-0012-6
Authors
- Publisher:
- SpringerOpen
- Host title:
- EJNMMI Radiopharmacy and Chemistry
- Journal:
- EJNMMI Radiopharmacy and Chemistry More from this journal
- Volume:
- 1 (Suppl 1)
- Issue:
- 10
- Pages:
- 12
- Series:
- 18th European Symposium on Radiopharmacy and Radiopharmaceuticals
- Publication date:
- 2016-06-17
- Acceptance date:
- 2016-01-04
- DOI:
- ISSN:
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2365-421X
- Pubs id:
-
pubs:691214
- UUID:
-
uuid:a2e2e8f8-4d8d-4e72-91f8-a28e8c519e67
- Local pid:
-
pubs:691214
- Source identifiers:
-
691214
- Deposit date:
-
2017-04-26
Terms of use
- Copyright holder:
- Song et al
- Copyright date:
- 2016
- Notes:
- © 2016 The Author(s). Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License.
- Licence:
- CC Attribution (CC BY)
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