Journal article

Organocatalytic highly enantioselective conjugate addition of aldehydes to alkylidine malonates

Abstract:: The first highly enantioselective, direct organocatalytic conjugate addition of unmodified aldehydes to alkylidinemalonates is presented. The reaction gives access to β-formyl-substituted malonates and highly functionalized lactones with up to 14:1 dr and generally 94 to >99% ee. © 2008 Wiley-VCH Verlag GmbH and Co. KGaA.

Publication status:: Published

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APA Style

Zhao, G., Vesely, J., Sun, J., Christensen, K., Bonneau, C., & Cordova, A. (2008). Organocatalytic highly enantioselective conjugate addition of aldehydes to alkylidine malonates. ADVANCED SYNTHESIS and CATALYSIS, 350(5), 657–661.

MLA Style

Zhao, G, et al. “Organocatalytic Highly Enantioselective Conjugate Addition of Aldehydes to Alkylidine Malonates.” ADVANCED SYNTHESIS and CATALYSIS, vol. 350, no. 5, 2008, pp. 657–61.

Chicago Style

Zhao, G, J Vesely, J Sun, K Christensen, C Bonneau, and A Cordova. 2008. “Organocatalytic Highly Enantioselective Conjugate Addition of Aldehydes to Alkylidine Malonates.” ADVANCED SYNTHESIS and CATALYSIS 350 (5): 657–61.
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Publisher copy:: 10.1002/adse.200700570

Authors

+ Zhao, G More by this author

Role:: Author

+ Vesely, J More by this author

Role:: Author

+ Sun, J More by this author

Role:: Author

+ Christensen, K More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Chemistry
Sub department:: Inorganic Chemistry
Role:: Author

+ Bonneau, C More by this author

Role:: Author

More authors...

Journal:: ADVANCED SYNTHESIS and CATALYSIS More from this journal
Volume:: 350
Issue:: 5
Pages:: 657-661
Publication date:: 2008-03-01
DOI:: 10.1002/adse.200700570
EISSN:: 1521-3897
ISSN:: 1615-4150

Language:: English
Keywords:: chiral lactones

aldehydes

alkylidenemalonates

conjugate additions

asymmetric catalysis
Pubs id:: pubs:321986
UUID:: uuid:a2af7585-ba59-4658-a09e-cf810475d9fe
Local pid:: pubs:321986
Source identifiers:: 321986
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_a2af7585ba594658a09ecf810475d9fe

Terms of use

Copyright date:: 2008

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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