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Determinants of survival without antiretroviral therapy after infancy in HIV-1-infected Zambian children in the CHAP Trial.

Abstract:

BACKGROUND: There are few data on predictors of HIV progression in untreated children in resource-limited settings. METHODS: Children with HIV Antibiotic Prophylaxis (CHAP) was a randomized trial comparing cotrimoxazole prophylaxis with placebo in HIV-infected Zambian children. The prognostic value of baseline characteristics was investigated using Cox models. RESULTS: Five hundred fourteen children aged 1 to 14 (median 5.5) years contributed 607 years follow-up (maximum 2.6 years). Half were...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Mulenga, V More by this author
Sinyinza, F More by this author
Lishimpi, K More by this author
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Journal:
Journal of acquired immune deficiency syndromes (1999)
Volume:
42
Issue:
5
Pages:
637-645
Publication date:
2006-08-05
DOI:
EISSN:
1944-7884
ISSN:
1525-4135
URN:
uuid:a297b8d4-2b11-41f2-bccd-b39936a62a7c
Source identifiers:
422648
Local pid:
pubs:422648

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