Visuo-spatial processing in autism - testing the predictions of extreme male brain theory

Journal article

It has been hypothesised that autism is an extreme version of the male brain, caused by high levels of prenatal testosterone (Baron-Cohen 1999). To test this proposal, associations were assessed between three visuo-spatial tasks and prenatal testosterone, indexed in second-to-fourth digit length ratios (2D:4D). The study included children with Autism Spectrum Disorder, ASD (N=28), and chronological as well as mental age matched typically-developing children (N=31). While the group with ASD outperformed the control group at Mental Rotation and Figure-Disembedding, these group differences were not related to differences in prenatal testosterone level. Previous findings of an association between Targeting and 2D:4D were replicated in typically-developing children and children with ASD. The implications of these results for the extreme male brain (EMB) theory of autism are discussed.

Authors: Falter, C; Plaisted, K; Davis, G

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Springer
• Journal: Journal of Autism and Developmental Disorders
• Volume: 38
• Issue: 3
• Pages: 507-515
• Publication date: 2008-01-01
• DOI: 10.1007/s10803-007-0419-8
• EISSN: 1573-3432
• ISSN: 0162-3257
• Language: English
• Keywords: extreme male brain; visuo-spatial cognition; autism; prenatal testosterone; 2D:4D
• Subjects: Autism