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Journal article

Benefits of using multiple first-line therapies against malaria.

Abstract:

Despite the availability of many drugs and therapies to treat malaria, many countries' national policies recommend using a single first-line therapy for most clinical malaria cases. To assess whether this is the best strategy for the population as a whole, we designed an evolutionary-epidemiological modeling framework for malaria and compared the benefits of different treatment strategies in the context of resistance evolution. Our results show that the population-wide use of multiple first-l...

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Publisher copy:
10.1073/pnas.0804628105

Authors


Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
105
Issue:
37
Pages:
14216-14221
Publication date:
2008-09-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:a218f284-c9a7-49c4-8081-d6992df31e53
Source identifiers:
125405
Local pid:
pubs:125405

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