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A crowd of BashTheBug volunteers reproducibly and accurately measure the minimum inhibitory concentrations of 13 antitubercular drugs from photographs of 96-well broth microdilution plates

Abstract:

Tuberculosis is a respiratory disease that is treatable with antibiotics. An increasing prevalence of resistance means that to ensure a good treatment outcome it is desirable to test the susceptibility of each infection to different antibiotics. Conventionally, this is done by culturing a clinical sample and then exposing aliquots to a panel of antibiotics, each being present at a pre-determined concentration, thereby determining if the sample isresistant or susceptible to each sample. The mi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.7554/eLife.75046

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author

Contributors

Publisher:
eLife Sciences Publications
Journal:
eLife More from this journal
Volume:
11
Article number:
e75046
Publication date:
2022-05-19
Acceptance date:
2022-05-15
DOI:
EISSN:
2050-084X
Language:
English
Keywords:
Pubs id:
1259805
Local pid:
pubs:1259805
Deposit date:
2022-05-16

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