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Efficacy and safety of once-daily single-inhaler triple therapy (FF/UMEC/VI) versus FF/VI in patients with inadequately controlled asthma (CAPTAIN): a double-blind, randomised, phase 3A trial

Abstract:

Background: Despite inhaled corticosteroid plus long-acting β2-agonist (ICS/LABA) therapy, 30–50% of patients with moderate or severe asthma remain inadequately controlled. We investigated the safety and efficacy of single-inhaler fluticasone furoate plus umeclidinium plus vilanterol (FF/UMEC/VI) compared with FF/VI.

Methods: In this double-blind, randomised, parallel-group, phase 3A study (Clinical Study in Asthma Pa...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/s2213-2600(20)30389-1

Authors



Publisher:
Elsevier
Journal:
Lancet More from this journal
Volume:
9
Issue:
1
Pages:
69-84
Publication date:
2020-09-09
Acceptance date:
2020-08-18
DOI:
EISSN:
2213-2619
ISSN:
2213-2600
Pmid:
32918892


Language:
English
Keywords:
Pubs id:
1132562
Local pid:
pubs:1132562
Deposit date:
2021-01-19

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