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Journal article

The genomic and epidemiological dynamics of human influenza A virus.

Abstract:

The evolutionary interaction between influenza A virus and the human immune system, manifest as 'antigenic drift' of the viral haemagglutinin, is one of the best described patterns in molecular evolution. However, little is known about the genome-scale evolutionary dynamics of this pathogen. Similarly, how genomic processes relate to global influenza epidemiology, in which the A/H3N2 and A/H1N1 subtypes co-circulate, is poorly understood. Here through an analysis of 1,302 complete viral genom...

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Publication status:
Published

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Publisher copy:
10.1038/nature06945

Authors


Rambaut, A More by this author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Nelson, MI More by this author
Taubenberger, JK More by this author
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Journal:
Nature
Volume:
453
Issue:
7195
Pages:
615-619
Publication date:
2008-05-05
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:a1ccaacf-ac63-4e81-a602-10e2f7ab2e77
Source identifiers:
130674
Local pid:
pubs:130674

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