- Abstract:
-
Islet amyloid polypeptide (IAPP) is the constituent peptide of amyloid in pancreatic islets of Type 2 diabetic patients and in insulinomas. Amyloid formation in Type 2 diabetes is associated with islet cell destruction which may promote formation of autoantibodies to IAPP. An ELISA method has been developed to detect IAPP autoantibodies and used to assay serum from 80 non-diabetic subjects, 49 Type 1 and 228 Type 2 diabetic patients, and 10 patients with insulinomas. Microtitre plates coated ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1111/j.1464-5491.1991.tb01675.x
-
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- Journal:
- Diabetic medicine : a journal of the British Diabetic Association
- Volume:
- 8
- Issue:
- 7
- Pages:
- 668-673
- Publication date:
- 1991-01-01
- DOI:
- EISSN:
-
1464-5491
- ISSN:
-
0742-3071
- URN:
-
uuid:a1914620-7875-45a3-9cdf-692c623e538d
- Source identifiers:
-
22210
- Local pid:
- pubs:22210
- Copyright date:
- 1991
Journal article
Autoantibodies to islet amyloid polypeptide in diabetes.
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