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Journal article

Unifying the spatial epidemiology and molecular evolution of emerging epidemics.

Abstract:

We introduce a conceptual bridge between the previously unlinked fields of phylogenetics and mathematical spatial ecology, which enables the spatial parameters of an emerging epidemic to be directly estimated from sampled pathogen genome sequences. By using phylogenetic history to correct for spatial autocorrelation, we illustrate how a fundamental spatial variable, the diffusion coefficient, can be estimated using robust nonparametric statistics, and how heterogeneity in dispersal can be rea...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.1206598109

Authors


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Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Role:
Author
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Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
109
Issue:
37
Pages:
15066-15071
Publication date:
2012-09-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:a165982d-d54e-414b-a3f9-b166ae71cf93
Source identifiers:
349872
Local pid:
pubs:349872

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