- Abstract:
-
In each influenza season, a distinct group of young, otherwise healthy individuals with no risk factors succumbs to life-threatening infection. To better understand the cause for this, we analyzed a broad range of immune responses in blood from a unique cohort of patients, comprising previously healthy individuals hospitalized with and without respiratory failure during one influenza season, and infected with one specific influenza A strain. This analysis was compared with similarly hospitali...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 1.6MB)
-
- Publisher copy:
- 10.1172/jci.insight.91868
-
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- Publisher:
- American Society for Clinical Investigation Publisher's website
- Journal:
- JCI Insight Journal website
- Volume:
- 2
- Issue:
- 7
- Pages:
- e91868
- Publication date:
- 2017-04-05
- DOI:
- EISSN:
-
2379-3708
- Pubs id:
-
pubs:691234
- URN:
-
uri:a11f53d5-7fd0-4467-a6ff-3dce7f542e46
- UUID:
-
uuid:a11f53d5-7fd0-4467-a6ff-3dce7f542e46
- Local pid:
- pubs:691234
- Language:
- English
- Keywords:
- Copyright holder:
- Dong et al
- Copyright date:
- 2017
- Notes:
- This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Journal article
M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza.
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Higher Education Funding Council for England
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Imperial College
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