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Cleavage specificities of the brother and sister proteases Lys-C and Lys-N.

Abstract:
Understanding of protease specificity is essential in proteomics strategies to correctly compare peptide fragmentation spectra with spectra predicted from data extracted from sequence databases. Here we evaluate the specificities of two proteolytic enzymes Lys-C and Lys-N, which cleave peptide-bonds at, respectively, the C- and N-terminal side of a lysine residue.
Publication status:
Published

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Publisher copy:
10.1039/c0cc02523b

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Role:
Author
Journal:
Chemical Communications More from this journal
Volume:
46
Issue:
46
Pages:
8827-8829
Publication date:
2010-12-01
DOI:
EISSN:
1364-548X
ISSN:
1359-7345
Language:
English
Keywords:
Pubs id:
pubs:384574
UUID:
uuid:a10aae69-705b-4c59-8c34-e00a3744331f
Local pid:
pubs:384574
Source identifiers:
384574
Deposit date:
2013-11-16

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