Journal article
Minimum efficacy criteria for comparisons between treatments using individual patient meta-analysis of acute pain trials: examples of etoricoxib, paracetamol, ibuprofen/paracetamol combinations after third molar extraction
- Abstract:
-
We defined response in acute pain trials to percentage of maximum possible efficacy. Minimum efficacy criteria (MEC) of 0%, or at least 15%, 30%, 50%, and 70% pain relief were used to examine stability over time using total pain relief and summed pain intensity difference (SPID), sex differences, and sensitivity. We used individual patient data from placebo-controlled third molar extraction trials: 4 with single-dose oral etoriocoxib 120 mg, and 2 with paracetamol, ibuprofen, and ibuprofen pl...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1016/j.pain.2010.11.030
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Authors
Contributors
Funding
Oxford Pain Relief Trust
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+ National Institute for Health Research Biomedical Research Centre Programme
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Funding agency for:
Moore, R
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Pain® Journal website
- Volume:
- 152
- Issue:
- 5
- Pages:
- 982-989
- Publication date:
- 2011-05-01
- DOI:
- ISSN:
-
0304-3959
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:a0ab5124-9ca5-4191-ae12-320e8c32af10
- Local pid:
- ora:5441
- Deposit date:
- 2011-06-10
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Terms of use
- Copyright holder:
- International Association for the Study of Pain
- Copyright date:
- 2010
- Notes:
- The full-text of this article is not available in ORA, but you may be able to access the article via the publisher copy link on this record page.
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