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Ankylosing spondylitis is associated with the anthrax toxin receptor 2 gene (ANTXR2).

Abstract:

OBJECTIVES: ANTXR2 variants have been associated with ankylosing spondylitis (AS) in two previous genome-wide association studies (GWAS) (p∼9×10(-8)). However, a genome-wide significant association (p<5×10(-8)) was not observed. We conducted a more comprehensive analysis of ANTXR2 in an independent UK sample to confirm and refine this association. METHODS: A replication study was carried out with 2978 cases and 8365 controls. Then, these were combined with non-overlapping samples from the ...

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Publication status:
Published

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Publisher:
BMJ Publishing Group
Journal:
Annals of the rheumatic diseases
Volume:
73
Issue:
11
Pages:
2054-2058
Publication date:
2014-11-05
DOI:
EISSN:
1468-2060
ISSN:
0003-4967
URN:
uuid:a0a4efd0-8a37-48b4-b2da-cbd834b44944
Source identifiers:
482533
Local pid:
pubs:482533

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