Journal article icon

Journal article

111In-BnDTPA-F3: An Auger electron-emitting radiotherapeutic agent that targets nucleolin

Abstract:

Introduction: The F3 peptide (KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK), a fragment of the human high mobility group protein 2, binds nucleolin. Nucleolin is expressed in the nuclei of normal cells but is also expressed on the membrane of some cancer cells. The goal was to investigate the use of 111In-labeled F3 peptide for Auger electron-targeted radiotherapy. Methods: F3 was labeled with fluorescein isothiocyanate (FITC) for confocal microscopy and conjugated to p-SCNbenzyl- diethylenetriaminepentaa...

Expand abstract

Actions


Access Document


Publisher copy:
10.1186/2191-219X-2-9

Authors


Expand authors...
Journal:
Dermatology and Therapy
Volume:
2
Issue:
1
Pages:
1-12
Publication date:
2012-01-01
DOI:
EISSN:
2190-9172
URN:
uuid:a03c4350-a753-4611-83c2-c40e17500c54
Source identifiers:
344636
Local pid:
pubs:344636
Language:
English
Keywords:

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP