Journal article
A population genetics-phylogenetics approach to inferring natural selection in coding sequences.
- Abstract:
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Through an analysis of polymorphism within and divergence between species, we can hope to learn about the distribution of selective effects of mutations in the genome, changes in the fitness landscape that occur over time, and the location of sites involved in key adaptations that distinguish modern-day species. We introduce a novel method for the analysis of variation in selection pressures within and between species, spatially along the genome and temporally between lineages. We model codon...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 504.4KB)
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- Publisher copy:
- 10.1371/journal.pgen.1002395
Authors
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Genetics Journal website
- Volume:
- 7
- Issue:
- 12
- Article number:
- e1002395
- Publication date:
- 2011-12-01
- DOI:
- EISSN:
-
1553-7404
- ISSN:
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1553-7390
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:a0384a57-d89d-49d9-aef3-f9074159716c
- Local pid:
- pubs:216148
- Source identifiers:
-
216148
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Wilson et al
- Copyright date:
- 2011
- Notes:
- Copyright 2011 Wilson et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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