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Preoperative sCD40L levels predict risk of atrial fibrillation after off-pump coronary artery bypass graft surgery.

Abstract:

BACKGROUND: The risk of atrial fibrillation (AF) after coronary bypass surgery has been related to redox state, inflammation, and ischemia. Platelet activation is common to all of these pathways. We investigated the relation between AF and preoperative soluble CD40 ligand (sCD40L), a proinflammatory marker released by activated platelets. Furthermore, we studied the role of inflammation, endothelial function, and redox state in this relation. METHODS AND RESULTS: sCD40L levels were measured i...

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Publication status:
Published

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Journal:
Circulation
Volume:
120
Issue:
11 Suppl
Pages:
S170-S176
Publication date:
2009-09-01
DOI:
EISSN:
1524-4539
ISSN:
0009-7322
Source identifiers:
104846

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