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New findings regarding the epidemic history and population dynamics of Japan-indigenous genotype 3 hepatitis E virus inferred by molecular evolution

Abstract:

Background: Since previous studies have investigated the population dynamics of Japan-indigenous genotype 3 hepatitis E virus (HEV) using virus sequences, more nucleotide sequences have been determined, and new techniques have been developed for such analysis. Aims: To prevent future hepatitis E epidemic in Japan, this study aimed to elucidate the cause of past HEV expansion. Methods: The epidemic history of Japan-indigenous genotype 3 HEV was determined using the coalescent analysis framewor...

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Authors


Takahashi, K More by this author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Hashimoto, N More by this author
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Journal:
Liver International
Volume:
32
Issue:
4
Pages:
675-688
Publication date:
2012-04-05
DOI:
EISSN:
1478-3231
ISSN:
1478-3223
URN:
uuid:9fdfc62c-c37b-4d0e-a6c7-90661e030f0e
Source identifiers:
321361
Local pid:
pubs:321361

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