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The use of microbeams to investigate radiation damage in living cells.

Abstract:
The micro-irradiation technique continues to be highly relevant to a number of radiobiological studies in vitro. In particular, studies of the bystander effect show that direct damage to cells is not the only trigger for radiation-induced effects, but that unirradiated cells can also respond to signals from irradiated neighbours. Furthermore, the bystander response can be initiated even when no energy is deposited in the genomic DNA of the irradiated cell (i.e. by targeting just the cytoplasm).
Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Role:
Author
Journal:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
Volume:
67
Issue:
3
Pages:
436-439
Publication date:
2009-03-05
DOI:
EISSN:
1872-9800
ISSN:
0969-8043
URN:
uuid:9fc905aa-77ec-4b5b-8fef-a67bb5f278cc
Source identifiers:
130837
Local pid:
pubs:130837
Language:
English
Keywords:

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