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IL-1R2-based biomarker models predict melioidosis mortality independent of clinical data

Abstract:

Introduction: Melioidosis is an often-fatal tropical infectious disease caused by the Gram-negative bacillus Burkholderia pseudomallei, but few studies have identified promising biomarker candidates to predict outcome.

Methods: In 78 prospectively enrolled patients hospitalized with melioidosis, six candidate protein biomarkers, identified from the literature, were measured in plasma at enrollment. A multi-biomarker model was developed using...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fmed.2023.1211265

Authors


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Research group:
MORU Mahidol-Oxford Tropical Medicine Research Unit
Role:
Author
More by this author
Research group:
MORU Mahidol-Oxford Tropical Medicine Research Unit
Role:
Author
Publisher:
Frontiers Media
Journal:
Frontiers in Medicine More from this journal
Volume:
10
Article number:
1211265
Place of publication:
Switzerland
Publication date:
2023-06-29
Acceptance date:
2023-06-06
DOI:
EISSN:
2296-858X
Pmid:
37457570
Language:
English
Keywords:
Pubs id:
1493638
Local pid:
pubs:1493638
Deposit date:
2023-09-20

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