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Chromosome abnormalities in the human oocyte.

Abstract:

Aneuploidy is the most commonly occurring type of chromosome abnormality and the most significant clinically. It arises mostly due to segregation errors taking place during female meiosis and is also closely associated with advancing maternal age. Two main aneuploidy-causing mechanisms have been described: the first involves the non-disjunction of entire chromosomes and can take place during both meiotic divisions, whereas the second involves the premature division of a chromosome into its 2 ...

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Publication status:
Published

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Publisher copy:
10.1159/000323801

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Institution:
University of Oxford
Department:
Oxford, MSD, Obstetrics and Gynaecology
Role:
Author
Journal:
Cytogenetic and genome research
Volume:
133
Issue:
2-4
Pages:
107-118
Publication date:
2011-01-01
DOI:
EISSN:
1424-859X
ISSN:
1424-8581
URN:
uuid:9f3c97ac-4745-4326-a4e8-e0869fcac7b7
Source identifiers:
248270
Local pid:
pubs:248270

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