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Journal article

Association of the BTNL2 rs2076530 single nucleotide polymorphism with Graves' disease appears to be secondary to DRB1 exon 2 position beta74.

Abstract:

OBJECTIVE: The HLA region encodes numerous immune response genes, with the DR/DQ molecules consistently associated with autoimmune disease (AID). Recent studies in sarcoidosis have identified association of a single nucleotide polymorphism (SNP) rs2076530 within BTNL2, a potential T-cell inhibitor, independent of the known DRB1 association. The aim of this study was to investigate the association rs2076530 with disease in a large UK Caucasian Graves' disease (GD) dataset. DESIGN: A case contr...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM
Role:
Author
Journal:
Clinical endocrinology
Volume:
65
Issue:
4
Pages:
429-432
Publication date:
2006-10-05
DOI:
EISSN:
1365-2265
ISSN:
0300-0664
URN:
uuid:9ec290fa-9d9c-4e7f-9705-bdab76ac558a
Source identifiers:
112430
Local pid:
pubs:112430

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