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A cost of illness analysis of children with encephalitis presenting to a major hospital in Vietnam

Abstract:

Encephalitis is a significant global health problem, especially in children. Knowledge of its economic burden is essential for policymakers in prioritizing the development and implementation of interventions but remains limited. An observational study was prospectively conducted at a major children’s hospital in Ho Chi Minh City, Vietnam from 2020 to 2022. Data on direct medical costs, direct nonmedical costs, and productivity costs were collected alongside demographic information, clinical features, diagnosis, severity, and outcomes of study participants. This was used to undertake a cost of illness analysis from a societal perspective. Data were collected from a total of 164 pediatric patients. The median cost of illness was estimated at USD1,859 (interquartile range [IQR]: USD1,273–USD3,128). The direct costs were the main cost driver, accounting for 83.9% of the total cost of illness (USD1,560; IQR: USD975–USD2,460). The productivity costs accounted for a median of USD275 (IQR: USD154–USD474). The cost of illness was higher in more severe patients, patients with sequelae, patients with morbidities, and ventilated patients. Most direct medical costs were attributed to hospitalization and resulted in out-of-pocket payments from the patient’s family (30.2%; USD316). The results showed that the cost of illness of encephalitis in children is considerable and will be useful for policymakers in prioritizing resources for the development and implementation of intervention strategies to reduce the burden of pediatric encephalitis.

Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.4269/ajtmh.24-0409

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Role:
Author
ORCID:
0000-0003-0904-9807


Publisher:
American Society of Tropical Medicine and Hygiene
Journal:
American Journal of Tropical Medicine and Hygiene More from this journal
Volume:
112
Issue:
2
Article number:
422-430
Publication date:
2024-11-19
Acceptance date:
2024-08-27
DOI:
EISSN:
1476-1645
ISSN:
0002-9637
Pmid:
39561390


Language:
English
Keywords:
Pubs id:
2064404
Local pid:
pubs:2064404
Deposit date:
2025-02-05
ARK identifier:

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