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Ectopic ACTH production by a bronchial carcinoid tumour responsive to desmopressin in vivo and in vitro.

Abstract:

A desmopressin-induced ACTH increase has been recently suggested to be specific for pituitary-dependent Cushing's disease. We present the case of a 47-year-old woman with Cushing's syndrome due to ectopic ACTH production by a bronchial carcinoid. While CRH failed to induce an ACTH or cortisol response, intravenous administration of desmopressin led to a 47% increase in serum ACTH and a 42% increase in serum cortisol concentration. After surgical removal of the tumour, the desmopressin respons...

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Publication status:
Published

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Authors


Callies, F More by this author
Nordmeyer, JP More by this author
Allolio, B More by this author
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Journal:
Clinical endocrinology
Volume:
47
Issue:
5
Pages:
623-627
Publication date:
1997-11-05
DOI:
EISSN:
1365-2265
ISSN:
0300-0664
URN:
uuid:9ea128fd-845b-4b6d-a78d-b14f0f438531
Source identifiers:
138539
Local pid:
pubs:138539

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