A longitudinal analysis of immune escapes from HLA-B*13-restricted T-cell responses at early stage of CRF01_AE subtype HIV-1 infection and implications for vaccine design

Journal article

Our study strongly suggested the inclusion of GI11 (Gag) and exclusion of RV9 (Nef) for T-cell-based vaccine design for B*13-positive CRF01_AE subtype HIV-1-infected MSM and high-risk individuals.

Authors: Zhang, H; He, C; Jiang, F; Cao, S; Zhao, B

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: BioMed Central
• Journal: BMC Immunology
• Volume: 23
• Issue: 1
• Pages: 15-15
• Article number: 15
• Publication date: 2022-04-02
• DOI: 10.1186/s12865-022-00491-7
• EISSN: 1471-2172
• ISSN: 1471-2172
• Language: English
• Keywords: Biology; Virology; Vaccine trial; Antibody; Antigen; Immune system; Immunology; Epitope; Cytotoxic T cell; HIV vaccine; Human leukocyte antigen; T cell; Genetics; ELISPOT; HLA-B Antigens