Journal article
Association of altered liver enzymes with Alzheimer disease diagnosis, cognition, neuroimaging measures, and cerebrospinal fluid biomarkers
- Abstract:
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Importance:Increasing evidence suggests an important role of liver function in the pathophysiology of Alzheimer disease (AD). The liver is a major metabolic hub; therefore, investigating the association of liver function with AD, cognition, neuroimaging, and CSF biomarkers would improve the understanding of the role of metabolic dysfunction in AD. Objective:To examine whether liver function markers are associated with cognitive dysfunction and the "A/T/N" (amyloid, tau, and neurodegeneration)...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 3.1MB, Terms of use)
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- Publisher copy:
- 10.1001/jamanetworkopen.2019.7978
Authors
Contributors
+ Alzheimer's Disease Neuroimaging Initiative
- Role:
- Contibutor
+ Alzheimer's Disease Metabolomics Consortium
- Role:
- Contibutor
- Publisher:
- JAMA Network
- Journal:
- JAMA Network Open More from this journal
- Volume:
- 2
- Issue:
- 7
- Article number:
- e197978
- Publication date:
- 2019-07-31
- Acceptance date:
- 2019-05-28
- DOI:
- EISSN:
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2574-3805
- Pmid:
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31365104
- Language:
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English
- Keywords:
- Pubs id:
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pubs:1037370
- UUID:
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uuid:9e76ffa8-be28-421a-9393-7d237c7bcfcd
- Local pid:
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pubs:1037370
- Source identifiers:
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1037370
- Deposit date:
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2019-11-19
- ARK identifier:
Terms of use
- Copyright date:
- 2019
- Notes:
- Open Access: This is an open access article distributed under the terms of the CC-BY License.
- Licence:
- CC Attribution (CC BY)
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