Journal article icon

Journal article

Zoledronic acid treatment of 5T2MM-bearing mice inhibits the development of myeloma bone disease: evidence for decreased osteolysis, tumor burden and angiogenesis, and increased survival.

Abstract:

Multiple myeloma is characterized by the growth of plasma cells in the bone marrow and the development of osteolytic bone disease. Myeloma cells are found closely associated with bone, and targeting this environment may therefore affect both the bone disease and the growth of myeloma cells. We have investigated the effect of the potent bisphosphonate, zoledronic acid, on the development of bone disease, tumor burden, and disease-free survival in the 5T2MM model of myeloma. 5T2MM murine myelom...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1359/jbmr.2003.18.3.482

Authors


Expand authors...
Journal:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Volume:
18
Issue:
3
Pages:
482-492
Publication date:
2003-03-05
DOI:
EISSN:
1523-4681
ISSN:
0884-0431
URN:
uuid:9e71e9b4-3c8c-420f-9ed9-e8f3cbfbb3f8
Source identifiers:
66430
Local pid:
pubs:66430

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP