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Hypothyroidism induces hyperplasia of unilocular adipocytes in perirenal adipose tissue of the ovine fetus

Abstract:
Thyroid hormones are important regulators of fetal growth, although their mechanism of action remains unclear. In the sheep fetus, thyroid hormone deficiency increases plasma insulin and leptin concentrations. This study investigated the effects of hypothyroidism on perirenal adipose tissue (PAT) development and adipose insulin signalling pathways in fetal sheep.
Publication status:
Published
Peer review status:
Reviewed (other)

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Publisher copy:
10.1530/endoabs.44.P235

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology Anatomy & Genetics
Role:
Author


Publisher:
Bioscientifica
Host title:
Society for Endocrinology BES 2016
Journal:
Society for Endocrinology BES 2016 More from this journal
Publication date:
2016-11-01
Acceptance date:
2016-06-15
DOI:
ISSN:
1479-6848


Pubs id:
pubs:743796
UUID:
uuid:9e71d94b-9328-44de-8b4e-3d559e8f02cb
Local pid:
pubs:743796
Source identifiers:
743796
Deposit date:
2018-03-06

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