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Free energy landscapes of DNA and its assemblies: perspectives from coarse-grained modelling

Abstract:
This chapter will provide an overview of how characterising free energy landscapes can provide insights into the biophysical properties of DNA, as well as into the behaviour of the DNA assemblies used in the field of DNA nanotechnology. The landscapes for these complex systems are accessible through the use of accurate coarse-grained descriptions of DNA. Particular foci will be the landscapes associated with DNA self-assembly and mechanical deformation, where the latter can arise from either externally imposed forces or internal stresses.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/b978-0-12-824406-7.00016-6

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Oxford college:
Queen's College
Role:
Author
ORCID:
0000-0002-2226-9524


Publisher:
Elsevier
Host title:
Frontiers of Nanoscience
Journal:
Frontiers of Nanoscience More from this journal
Volume:
21
Pages:
195-210
Publication date:
2022-06-09
DOI:
ISSN:
876-2778


Language:
English
Keywords:
Pubs id:
1211687
Local pid:
pubs:1211687
Deposit date:
2022-06-12

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