- Abstract:
-
Prostate cancer (PCa) is the most common non-cutaneous cancer in men. The androgen receptor (AR), a ligand-activated transcription factor, constitutes the main drug target for advanced cases of the disease. However, a variety of other transcription factors and signaling networks have been shown to be altered in patients and to influence AR activity. Amongst these, the oncogenic transcription factor c-Myc has been studied extensively in multiple malignancies and elevated protein levels of c-My...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 1.8mb)
-
- Publisher copy:
- 10.1016/j.ebiom.2017.04.006
-
Version unsuitable
-
We have not obtained a suitable full-text for a given research output. See this page for more information.
-
Recently completed
-
Sometimes content is held in ORA but is unavailable for a fixed period of time to comply with the policies and wishes of rights holders.
-
Permissions
-
All content made available in ORA should comply with relevant rights, such as copyright. See this page for more information.
-
Clearance
-
Some thesis volumes scanned as part of the digitisation scheme funded by Dr Leonard Polonsky are currently unavailable due to sensitive material or uncleared third-party copyright content. We are attempting to contact authors whose theses are affected.
- Publisher:
- Elsevier Publisher's website
- Journal:
- EBioMedicine Journal website
- Volume:
- 18
- Pages:
- 83-93
- Publication date:
- 2017-04-05
- Acceptance date:
- 2017-04-04
- DOI:
- EISSN:
-
2352-3964
- Pubs id:
-
pubs:817470
- URN:
-
uri:9e3b262c-6991-4e69-b56d-4e146e163d06
- UUID:
-
uuid:9e3b262c-6991-4e69-b56d-4e146e163d06
- Local pid:
- pubs:817470
- Copyright holder:
- Crown Copyright
- Copyright date:
- 2017
- Notes:
- Crown Copyright © 2017 Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Journal article
c-Myc antagonises the transcriptional activity of the androgen receptor in prostate cancer affecting key gene networks.
Actions
Access Document
Why is the content I wish to access not available via ORA?
Bibliographic data (the information relating to research outputs) and full-text items (e.g. articles, theses, reports, etc.) arrive in ORA from several different sources. Unfortunately we are not able to make available the full-text for every research output.
Please contact the ORA team (
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
Content may be unavailable for the following four reasons
Alternative access to the full-text
You may be able to access the full-text directly from the publisher's website using the 'Publisher Copy' link in the 'Links & Downloads' box from a research output's ORA record page. This method may require an institutional or individual subscription to the journal/resource.
Authors
Funding
Norwegian Cancer Society
More from this funder
South-East Norway Health Authorities
More from this funder
Norwegian Centre for Molecular Medicine
More from this funder
Norwegian Research Council
More from this funder
Norwegian Cancer Society
More from this funder
Expand funders...
Bibliographic Details
Item Description
Terms of use
Metrics
Altmetrics
Dimensions
If you are the owner of this record, you can report an update to it here: Report update to this record