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Journal article

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.

Abstract:

Using the ImmunoChip custom genotyping array, we analyzed 14,498 subjects with multiple sclerosis and 24,091 healthy controls for 161,311 autosomal variants and identified 135 potentially associated regions (P < 1.0 × 10(-4)). In a replication phase, we combined these data with previous genome-wide association study (GWAS) data from an independent 14,802 subjects with multiple sclerosis and 26,703 healthy controls. In these 80,094 individuals of European ancestry, we identified 48 new susc...

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Publication status:
Published

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Publisher copy:
10.1038/ng.2770

Authors


Beecham, AH More by this author
Patsopoulos, NA More by this author
Xifara, DK More by this author
Kemppinen, A More by this author
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Journal:
Nature genetics
Volume:
45
Issue:
11
Pages:
1353-1360
Publication date:
2013-11-05
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
URN:
uuid:9e2aafb8-d84c-4c71-8cfd-ce4d320b4853
Source identifiers:
431143
Local pid:
pubs:431143

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