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Gonococcal cervicitis is associated with reduced systemic CD8+ T cell responses in human immunodeficiency virus type 1-infected and exposed, uninfected sex workers.

Abstract:

Neisseria gonorrhoeae cervicitis and human immunodeficiency virus (HIV) type 1 frequently coinfect core transmitter populations, such as female sex workers. Gonococcal cervicitis is associated with increased viral shedding and plasma viremia in HIV-1-infected women and increased HIV-1 susceptibility in uninfected women. We studied the influence of gonococcal cervicitis on CD8(+) interferon (IFN)-gamma responses to HIV-1 and cytomegalovirus (CMV) epitopes in HIV-1-infected and in highly-expose...

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Publication status:
Published

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Publisher copy:
10.1086/340214

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine
Role:
Author
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Journal:
The Journal of infectious diseases
Volume:
185
Issue:
10
Pages:
1525-1529
Publication date:
2002-05-05
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
URN:
uuid:9d20d166-36c3-4fbe-9a48-ebb0879b0da5
Source identifiers:
31148
Local pid:
pubs:31148

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