Journal article icon

Journal article

Three-dimensional structures of translating ribosomes by Cryo-EM.

Abstract:

Cryo-electron microscopy and image reconstruction techniques have been used to obtain three-dimensional maps for E. coli ribosomes stalled following translation of three representative proteins. Comparisons of these electron density maps, at resolutions of between 13 and 16 A, with that of a nontranslating ribosome pinpoint specific structural differences in stalled ribosomes and identify additional material, including tRNAs and mRNA. In addition, the tunnel through the large subunit, the ant...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Structural Biology
Connell, S More by this author
Fuller, SD More by this author
Nierhaus, KH More by this author
Expand authors...
Journal:
Molecular cell
Volume:
14
Issue:
1
Pages:
57-66
Publication date:
2004-04-05
DOI:
EISSN:
1097-4164
ISSN:
1097-2765
URN:
uuid:9d102e55-5701-4209-87b8-c55678131263
Source identifiers:
27194
Local pid:
pubs:27194

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP