Journal article
Iminosugar NB-DNJ delays mortality in lethal model of dengue virus infection in mice
- Abstract:
- The four serotypes of dengue virus (DV1-4) cause more human illness than any other arbovirus worldwide. DV infection results in dengue fever, an acute febrile illness, or the more severe, life-threatening dengue hemorrhagic fever/dengue shock. We have developed a robust mouse model of DV infection and disease in mice lacking interferon α/β and γ receptors (AG129) that features many of the hallmarks of severe dengue in humans.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
- Publisher:
- American Society of Tropical Medicine and Hygiene
- Journal:
- American Journal of Tropical Medicine and Hygiene More from this journal
- Volume:
- 81
- Issue:
- 5
- Pages:
- 123-123
- Publication date:
- 2009-11-01
- EISSN:
-
1476-1645
- ISSN:
-
0002-9637
- Pubs id:
-
pubs:100441
- UUID:
-
uuid:9ce053b7-67bc-4535-8aca-214288b12123
- Local pid:
-
pubs:100441
- Source identifiers:
-
100441
- Deposit date:
-
2012-12-19
Terms of use
- Copyright holder:
- American Society of Tropical Medicine and Hygiene
- Copyright date:
- 2009
- Notes:
- Copyright © 2009 by the American Society of Tropical Medicine and Hygiene. This is the publisher's version of the article. The final version is available online from the American Society of Tropical Medicine and Hygiene at: [http://www.ajtmh.org/content/81/5_Suppl_1]
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