BACKGROUND: Low muscle mass and function have been associated with poorer indicators of physical capability in older people, which are in-turn associated with increased mortality rates. The growth hormone/insulin-like growth factor (GH/IGF) axis is involved in muscle function and genetic variants in genes in the axis may influence measures of physical capability. METHODS: As part of the Healthy Ageing across the Life Course (HALCyon) programme, men and women from seven UK cohorts aged between...Expand abstract
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A multi-cohort study of polymorphisms in the GH/IGF axis and physical capability: the HALCyon programme.
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