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A multi-cohort study of polymorphisms in the GH/IGF axis and physical capability: the HALCyon programme.

Abstract:

BACKGROUND: Low muscle mass and function have been associated with poorer indicators of physical capability in older people, which are in-turn associated with increased mortality rates. The growth hormone/insulin-like growth factor (GH/IGF) axis is involved in muscle function and genetic variants in genes in the axis may influence measures of physical capability. METHODS: As part of the Healthy Ageing across the Life Course (HALCyon) programme, men and women from seven UK cohorts aged between...

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Publication status:
Published

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Publisher copy:
10.1371/journal.pone.0029883

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
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Journal:
PloS one
Volume:
7
Issue:
1
Pages:
e29883
Publication date:
2012-01-01
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
URN:
uuid:9ca6f403-e5d3-493e-8338-139debb8bcf4
Source identifiers:
254342
Local pid:
pubs:254342

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