Journal article

Synthesis of phenylglycine derivatives as potent and selective antagonists of group III metabotropic glutamate receptors.

Abstract:: The syntheses of a range of ring and alpha-substituted 4-phosphonophenylglycines are described. A brief discussion of the antagonist activities of compounds 4-10 on group I, II and III metabotropic glutamate (mGlu) receptors expressed in the neonatal rat spinal cord is included.

Publication status:: Published

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APA Style

Conway, S., Miller, J., Howson, P., Clark, B., & Jane, D. (2001). Synthesis of phenylglycine derivatives as potent and selective antagonists of group III metabotropic glutamate receptors. Bioorganic and Medicinal Chemistry Letters, 11(6), 777–780.

MLA Style

Conway, S, et al. “Synthesis of Phenylglycine Derivatives as Potent and Selective Antagonists of Group III Metabotropic Glutamate Receptors.” Bioorganic and Medicinal Chemistry Letters, vol. 11, no. 6, 2001, pp. 777–80.

Chicago Style

Conway, S, J Miller, P Howson, B Clark, and D Jane. 2001. “Synthesis of Phenylglycine Derivatives as Potent and Selective Antagonists of Group III Metabotropic Glutamate Receptors.” Bioorganic and Medicinal Chemistry Letters 11 (6): 777–80.
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Publisher copy:: 10.1016/s0960-894x(01)00052-x

Authors

+ Conway, S More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Chemistry
Sub department:: Organic Chemistry
Role:: Author

+ Miller, J More by this author

Role:: Author

+ Howson, P More by this author

Role:: Author

+ Clark, B More by this author

Role:: Author

+ Jane, D More by this author

Role:: Author

Journal:: Bioorganic and medicinal chemistry letters More from this journal
Volume:: 11
Issue:: 6
Pages:: 777-780
Publication date:: 2001-03-01
DOI:: 10.1016/s0960-894x(01)00052-x
EISSN:: 1464-3405
ISSN:: 0960-894X

Language:: English
Keywords:: Rats, Wistar

Receptors, Metabotropic Glutamate

Structure-Activity Relationship

Male

Rats

Animals

Excitatory Amino Acid Antagonists

Female

Glycine
Pubs id:: pubs:52003
UUID:: uuid:9c91a7d5-2f5f-422d-928c-e2387c760c17
Local pid:: pubs:52003
Source identifiers:: 52003
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_9c91a7d52f5f422d928ce2387c760c17

Terms of use

Copyright date:: 2001

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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