Journal article

Anaphylactoid reactions and angioedema during alteplase treatment of acute ischemic stroke.

Abstract:: Among 105 patients given recombinant tissue plasminogen activator (rt-PA, alteplase) intravenously for acute stroke, 2 (1.9%) had lingual angioedema, which progressed to a fatal anaphylactoid reaction in 1. The authors review the 2 cases and possible mechanisms responsible. They warn that patients who are taking an angiotensin-converting-enzyme inhibitor may be at increased risk for angioedema with concomitant alteplase therapy.

Publication status:: Published

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APA Style

Hill, M. D., Barber, P., Takahashi, J., Demchuk, A., Feasby, T., & Buchan, A. (2000). Anaphylactoid reactions and angioedema during alteplase treatment of acute ischemic stroke. CMAJ : Canadian Medical Association Journal = Journal De l'Association Medicale Canadienne, 162(9), 1281–1284.

MLA Style

Hill, M. D., et al. “Anaphylactoid Reactions and Angioedema during Alteplase Treatment of Acute Ischemic Stroke.” CMAJ : Canadian Medical Association Journal = Journal De l'Association Medicale Canadienne, vol. 162, no. 9, 2000, pp. 1281–84.

Chicago Style

Hill, MD, P Barber, J Takahashi, A Demchuk, T Feasby, and A Buchan. 2000. “Anaphylactoid Reactions and Angioedema during Alteplase Treatment of Acute Ischemic Stroke.” CMAJ : Canadian Medical Association Journal = Journal De l'Association Medicale Canadienne 162 (9): 1281–84.
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Authors

+ Hill, MD More by this author

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+ Barber, P More by this author

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+ Takahashi, J More by this author

Role:: Author

+ Demchuk, A More by this author

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+ Feasby, T More by this author

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Journal:: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne More from this journal
Volume:: 162
Issue:: 9
Pages:: 1281-1284
Publication date:: 2000-05-01
EISSN:: 1488-2329
ISSN:: 0820-3946

Language:: English
Keywords:: Humans

Female

Thrombolytic Therapy

Angioedema

Aged

Drug Hypersensitivity

Anaphylaxis

Cerebral Infarction

Tissue Plasminogen Activator

Diagnosis, Differential

Infusions, Intravenous
Pubs id:: pubs:79079
UUID:: uuid:9c5c1f7c-0011-4be2-b31b-0bc5f6085cda
Local pid:: pubs:79079
Source identifiers:: 79079
Deposit date:: 2012-12-19

Terms of use

Copyright date:: 2000

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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