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Journal article

Comparison of two schedules of two-dose priming with the ten-valent pneumococcal conjugate vaccine in Nepalese children: an open-label, randomised non-inferiority controlled trial

Abstract:

Background

Nepalese infants receive ten-valent pneumococcal conjugate vaccine (PCV10) with a 1 month interval between priming doses for programmatic reasons. We aimed to investigate whether immune responses to PCV10 serotypes were non-inferior if the second priming dose of PCV10 was delivered at a 1 month interval as opposed to a 2 month interval.

Methods

We did an open-label, randomised, parallel group trial in healthy Nepalese infants aged 40–60 days at Patan Hospita...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/s1473-3099(18)30568-1

Authors

More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Department of Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Primary Care Health Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Primary Care Health Sciences
Role:
Author


Publisher:
Elsevier
Journal:
Lancet: Infectious Diseases More from this journal
Volume:
19
Issue:
2
Pages:
156-164
Publication date:
2019-01-08
Acceptance date:
2018-09-11
DOI:
EISSN:
1474-4457
ISSN:
1473-3099
Pmid:
30635252


Language:
English
Pubs id:
pubs:959581
UUID:
uuid:9c574e7e-817a-42b5-a2a9-1725227f2bc9
Local pid:
pubs:959581
Source identifiers:
959581
Deposit date:
2019-01-15
ARK identifier:

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